Diagnostic Value of a PCR-Based Technique for Prosthetic Joint Infection

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چکیده

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Diagnostic value of a PCR-based technique for prosthetic joint infection.

Prosthetic joint infection (PJI) is a catastrophic complication for patients with arthroplasty. Culture is the most commonly used method to identify PJI. However, it may not be accurate enough because of contamination and false-negative results (1). A PCR-based technique has been developed and provides great value for PJI diagnosis. Thus, we read with great interest the study by Qu et al. (2) e...

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Reply to "Diagnostic value of a PCR-based technique for prosthetic joint infection".

We greatly appreciate the interest of Li and Yu (1) in our article (2) that evaluated the use of PCR assays for diagnosis of prosthetic joint infection (PJI). In their letter, Li and Yu raised some thoughtful comments regarding the selection of the included studies and performed an updated meta-analysis. They indicated that two similar studies (3, 4) by Kobayashi et al. were performed during th...

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PCR-based diagnosis of prosthetic joint infection.

We performed a meta-analysis to evaluate use of PCR assays for diagnosis of prosthetic joint infection (PJI). The pooled sensitivity and specificity were 0.86 (95% confidence interval [CI], 0.77 to 0.92) and 0.91 (CI, 0.81 to 0.96), respectively. Subgroup analyses showed that use of tissue samples may improve sensitivity, and quantitative PCR and sonication of prostheses fluid may improve speci...

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Prosthetic joint infection development of an evidence-based diagnostic algorithm

BACKGROUND Increasing rates of prosthetic joint infection (PJI) have presented challenges for general practitioners, orthopedic surgeons and the health care system in the recent years. The diagnosis of PJI is complex; multiple diagnostic tools are used in the attempt to correctly diagnose PJI. Evidence-based algorithms can help to identify PJI using standardized diagnostic steps. METHODS We r...

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Preoperative Aspiration Culture (PAC) for the Diagnosis of Infection in a Prosthetic Knee Joint

Background: Periprosthetic infection is the most serious joint replacement complication, occurring in 0.8-1.9% of totalknee arthroplasties (TKAs).This review aims to define the role of preoperative aspiration culture (PAC) for diagnosis of TKA infection.Methods: A PubMed (MEDLINE) search related to TKA infection and PAC was analyzed. The main criteria for selectionwere that the articles were fo...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2014

ISSN: 0095-1137

DOI: 10.1128/jcm.00840-14